Cargando…
Chronic cAMP activation induces adipocyte browning through discordant biphasic remodeling of transcriptome and chromatin accessibility
OBJECTIVE: Adipose tissue thermogenesis has been suggested as a new therapeutic target to promote energy metabolism for obesity and metabolic disease. Cold-inducible thermogenic adipocytes, called beige adipocytes, have attracted significant attention for their potent anti-obesity activity in adult...
Autores principales: | So, Jisun, Taleb, Solaema, Wann, Jamie, Strobel, Olivia, Kim, Kyungchan, Roh, Hyun Cheol |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636484/ https://www.ncbi.nlm.nih.gov/pubmed/36273781 http://dx.doi.org/10.1016/j.molmet.2022.101619 |
Ejemplares similares
-
cGMP and cAMP differentially regulate differentiation and function of brown adipocytes
por: Jennissen, Katja, et al.
Publicado: (2011) -
Secretory Proteome of Brown Adipocytes in Response to cAMP-Mediated Thermogenic Activation
por: Villarroya, Joan, et al.
Publicado: (2019) -
CFTR regulates brown adipocyte thermogenesis via the cAMP/PKA signaling pathway
por: Choi, Kyung-Mi, et al.
Publicado: (2023) -
Uncoupling protein 1-driven Cre (Ucp1-Cre) is expressed in the epithelial cells of mammary glands and various non-adipose tissues
por: Kim, Kyungchan, et al.
Publicado: (2023) -
Adipocytes fail to maintain cellular identity during obesity due to reduced PPARγ activity and elevated TGFβ-SMAD signaling
por: Roh, Hyun Cheol, et al.
Publicado: (2020)