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Reciprocal interactions among Cobll1, PACSIN2, and SH3BP1 regulate drug resistance in chronic myeloid leukemia

Cobll1 affects blast crisis (BC) progression and tyrosine kinase inhibitor (TKI) resistance in chronic myeloid leukemia (CML). PACSIN2, a novel Cobll1 binding protein, activates TKI‐induced apoptosis in K562 cells, and this activation is suppressed by Cobll1 through the interaction between PACSIN2 a...

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Detalles Bibliográficos
Autores principales: Park, Kibeom, Yoo, Hee‐Seop, Oh, Chang‐Kyu, Lee, Joo Rak, Chung, Hee Jin, Kim, Ha‐Neul, Kim, Soo‐Hyun, Kee, Kyung‐Mi, Kim, Tong Yoon, Kim, Myungshin, Kim, Byung‐Gyu, Ra, Jae Sun, Myung, Kyungjae, Kim, Hongtae, Han, Seung Hun, Seo, Min‐Duk, Lee, Yoonsung, Kim, Dong‐Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636508/
https://www.ncbi.nlm.nih.gov/pubmed/35352878
http://dx.doi.org/10.1002/cam4.4727