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A practical framework RNMF for exploring the association between mutational signatures and genes using gene cumulative contribution abundance

BACKGROUND: Mutational signatures are somatic mutation patterns enriching operational mutational processes, which can provide abundant information about the mechanism of cancer. However, understanding of the pathogenic biological processes is still limited, such as the association between mutational...

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Detalles Bibliográficos
Autores principales: Li, Zhenzhang, Liang, Haihua, Zhang, Shaoan, Luo, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636515/
https://www.ncbi.nlm.nih.gov/pubmed/35575002
http://dx.doi.org/10.1002/cam4.4717