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A practical framework RNMF for exploring the association between mutational signatures and genes using gene cumulative contribution abundance
BACKGROUND: Mutational signatures are somatic mutation patterns enriching operational mutational processes, which can provide abundant information about the mechanism of cancer. However, understanding of the pathogenic biological processes is still limited, such as the association between mutational...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636515/ https://www.ncbi.nlm.nih.gov/pubmed/35575002 http://dx.doi.org/10.1002/cam4.4717 |