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Acute liver failure associated with lamotrigine in children with epilepsy: A report of two cases and thoughts on pharmacogenomics

Pediatric acute liver failure (PALF) is a rare and life-threatening clinical syndrome for which drug-induced liver injury is a cause. Lamotrigine (LTG) is generally a safe and effective antiseizure medication, and PALF related to LTG has rarely been reported. Here, we describe two cases of PALF asso...

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Detalles Bibliográficos
Autores principales: Deng, Jie, Fu, Zheng-ran, Wang, Long, Liu, Jun, Chen, Chun-hong, Fang, Fang, Wang, Xiao-ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636542/
https://www.ncbi.nlm.nih.gov/pubmed/36345310
http://dx.doi.org/10.1016/j.ebr.2022.100568