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Using reporters of different misfolded proteins reveals differential strategies in processing protein aggregates

The accumulation of misfolded proteins is a hallmark of aging and many neurodegenerative diseases, making it important to understand how the cellular machinery recognizes and processes such proteins. A key question in this respect is whether misfolded proteins are handled in a similar way regardless...

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Detalles Bibliográficos
Autores principales: Schneider, Kara L., Ahmadpour, Doryaneh, Keuenhof, Katharina S., Eisele-Bürger, Anna Maria, Berglund, Lisa Larsson, Eisele, Frederik, Babazadeh, Roja, Höög, Johanna L., Nyström, Thomas, Widlund, Per O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636550/
https://www.ncbi.nlm.nih.gov/pubmed/36096201
http://dx.doi.org/10.1016/j.jbc.2022.102476