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Improved mammalian retromer cryo-EM structures reveal a new assembly interface

Retromer (VPS26/VPS35/VPS29 subunits) assembles with multiple sorting nexin proteins on membranes to mediate endosomal recycling of transmembrane protein cargoes. Retromer has been implicated in other cellular processes, including mitochondrial homeostasis, nutrient sensing, autophagy, and fission e...

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Detalles Bibliográficos
Autores principales: Kendall, Amy K., Chandra, Mintu, Xie, Boyang, Wan, William, Jackson, Lauren P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636581/
https://www.ncbi.nlm.nih.gov/pubmed/36174678
http://dx.doi.org/10.1016/j.jbc.2022.102523