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Lactic acid bacteria–derived γ-linolenic acid metabolites are PPARδ ligands that reduce lipid accumulation in human intestinal organoids

Gut microbiota regulate physiological functions in various hosts, such as energy metabolism and immunity. Lactic acid bacteria, including Lactobacillus plantarum, have a specific polyunsaturated fatty acid saturation metabolism that generates multiple fatty acid species, such as hydroxy fatty acids,...

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Detalles Bibliográficos
Autores principales: Noguchi, Makoto, Shimizu, Makoto, Lu, Peng, Takahashi, Yu, Yamauchi, Yoshio, Sato, Shintaro, Kiyono, Hiroshi, Kishino, Shigenobu, Ogawa, Jun, Nagata, Koji, Sato, Ryuichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636582/
https://www.ncbi.nlm.nih.gov/pubmed/36162507
http://dx.doi.org/10.1016/j.jbc.2022.102534