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Lactic acid bacteria–derived γ-linolenic acid metabolites are PPARδ ligands that reduce lipid accumulation in human intestinal organoids
Gut microbiota regulate physiological functions in various hosts, such as energy metabolism and immunity. Lactic acid bacteria, including Lactobacillus plantarum, have a specific polyunsaturated fatty acid saturation metabolism that generates multiple fatty acid species, such as hydroxy fatty acids,...
Autores principales: | Noguchi, Makoto, Shimizu, Makoto, Lu, Peng, Takahashi, Yu, Yamauchi, Yoshio, Sato, Shintaro, Kiyono, Hiroshi, Kishino, Shigenobu, Ogawa, Jun, Nagata, Koji, Sato, Ryuichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636582/ https://www.ncbi.nlm.nih.gov/pubmed/36162507 http://dx.doi.org/10.1016/j.jbc.2022.102534 |
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