Irradiation-induced exosomal HMGB1 to confer radioresistance via the PI3K/AKT/FOXO3A signaling pathway in ESCC

BACKGROUND: Radioresistance is a major cause of treatment failure in esophageal squamous cell carcinoma (ESCC) radiotherapy, and the underlying mechanisms of radioresistance are still unclear. Irradiation (IR) stimulates changes in tumor-derived exosome contents, which can be taken up by recipient c...

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Detalles Bibliográficos
Autores principales: Du, Xingyu, Zhang, Xueyuan, Dong, Jing, Zou, Naiyi, Guo, Dong, Yao, Weinan, Wang, Xiaobin, Li, Shuguang, Song, Chunyang, Yan, Ke, Shen, Wenbin, Zhu, Shuchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636677/
https://www.ncbi.nlm.nih.gov/pubmed/36335371
http://dx.doi.org/10.1186/s12967-022-03720-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636677/
https://www.ncbi.nlm.nih.gov/pubmed/36335371
http://dx.doi.org/10.1186/s12967-022-03720-0

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