Stem cell phenotype predicts therapeutic response in glioblastomas with MGMT promoter methylation

A growing body of evidence supports the presence of a population of cells in glioblastoma (GBM) with a stem cell-like phenotype which shares certain biological markers with adult neural stem cells, including expression of SOX2, CD133 (PROM1), and NES (nestin). This study was designed to determine th...

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Detalles Bibliográficos
Autores principales: Lakis, Nelli S., Brodsky, Alexander S., Karashchuk, Galina, Audesse, Amanda J., Yang, Dongfang, Sturtevant, Ashlee, Lombardo, Kara, Wong, Ian Y., Webb, Ashley E., Anthony, Douglas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636755/
https://www.ncbi.nlm.nih.gov/pubmed/36333778
http://dx.doi.org/10.1186/s40478-022-01459-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636755/
https://www.ncbi.nlm.nih.gov/pubmed/36333778
http://dx.doi.org/10.1186/s40478-022-01459-9

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