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Stem cell phenotype predicts therapeutic response in glioblastomas with MGMT promoter methylation

A growing body of evidence supports the presence of a population of cells in glioblastoma (GBM) with a stem cell-like phenotype which shares certain biological markers with adult neural stem cells, including expression of SOX2, CD133 (PROM1), and NES (nestin). This study was designed to determine th...

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Detalles Bibliográficos
Autores principales:	Lakis, Nelli S., Brodsky, Alexander S., Karashchuk, Galina, Audesse, Amanda J., Yang, Dongfang, Sturtevant, Ashlee, Lombardo, Kara, Wong, Ian Y., Webb, Ashley E., Anthony, Douglas C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636755/ https://www.ncbi.nlm.nih.gov/pubmed/36333778 http://dx.doi.org/10.1186/s40478-022-01459-9

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