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Deciphering the impact of genetic variation on human polyadenylation using APARENT2
BACKGROUND: 3′-end processing by cleavage and polyadenylation is an important and finely tuned regulatory process during mRNA maturation. Numerous genetic variants are known to cause or contribute to human disorders by disrupting the cis-regulatory code of polyadenylation signals. Yet, due to the co...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636789/ https://www.ncbi.nlm.nih.gov/pubmed/36335397 http://dx.doi.org/10.1186/s13059-022-02799-4 |