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Fetuin-A alleviates neuroinflammation against traumatic brain injury-induced microglial necroptosis by regulating Nrf-2/HO-1 pathway

BACKGROUND: The microglia-mediated inflammatory response is a vital mechanism of secondary damage following traumatic brain injury (TBI), but the underlying mechanism of microglial activation is unclear. METHODS: Controlled cortical impact (CCI) was induced in adult male C57BL/6J mice, and glutamate...

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Detalles Bibliográficos
Autores principales: Zhao, Pengzhan, Wei, Yutian, Sun, Guangchi, Xu, Lei, Wang, Tian, Tian, Yufei, Chao, Honglu, Tu, Yiming, Ji, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636801/
https://www.ncbi.nlm.nih.gov/pubmed/36333786
http://dx.doi.org/10.1186/s12974-022-02633-5