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Neurons derived from individual early Alzheimer’s disease patients reflect their clinical vulnerability

Establishing preclinical models of Alzheimer’s disease that predict clinical outcomes remains a critically important, yet to date not fully realized, goal. Models derived from human cells offer considerable advantages over non-human models, including the potential to reflect some of the inter-indivi...

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Detalles Bibliográficos
Autores principales: Ng, Bryan, Rowland, Helen A, Wei, Tina, Arunasalam, Kanisa, Hayes, Emma Mee, Koychev, Ivan, Hedegaard, Anne, Ribe, Elena M, Chan, Dennis, Chessell, Tharani, Ffytche, Dominic, Gunn, Roger N, Kocagoncu, Ece, Lawson, Jennifer, Malhotra, Paresh A, Ridha, Basil H, Rowe, James B, Thomas, Alan J, Zamboni, Giovanna, Buckley, Noel J, Cader, Zameel M, Lovestone, Simon, Wade-Martins, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636855/
https://www.ncbi.nlm.nih.gov/pubmed/36349119
http://dx.doi.org/10.1093/braincomms/fcac267