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Neurons derived from individual early Alzheimer’s disease patients reflect their clinical vulnerability
Establishing preclinical models of Alzheimer’s disease that predict clinical outcomes remains a critically important, yet to date not fully realized, goal. Models derived from human cells offer considerable advantages over non-human models, including the potential to reflect some of the inter-indivi...
Autores principales: | Ng, Bryan, Rowland, Helen A, Wei, Tina, Arunasalam, Kanisa, Hayes, Emma Mee, Koychev, Ivan, Hedegaard, Anne, Ribe, Elena M, Chan, Dennis, Chessell, Tharani, Ffytche, Dominic, Gunn, Roger N, Kocagoncu, Ece, Lawson, Jennifer, Malhotra, Paresh A, Ridha, Basil H, Rowe, James B, Thomas, Alan J, Zamboni, Giovanna, Buckley, Noel J, Cader, Zameel M, Lovestone, Simon, Wade-Martins, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636855/ https://www.ncbi.nlm.nih.gov/pubmed/36349119 http://dx.doi.org/10.1093/braincomms/fcac267 |
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