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The role of GTP hydrolysis by EF-G in ribosomal translocation

Translocation of transfer RNA (tRNA) and messenger RNA (mRNA) through the ribosome is catalyzed by the GTPase elongation factor G (EF-G) in bacteria. Although guanosine-5'-triphosphate (GTP) hydrolysis accelerates translocation and is required for dissociation of EF-G, its fundamental role rema...

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Detalles Bibliográficos
Autores principales: Rexroad, Gillian, Donohue, John Paul, Lancaster, Laura, Noller, Harry F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636962/
https://www.ncbi.nlm.nih.gov/pubmed/36282914
http://dx.doi.org/10.1073/pnas.2212502119