HOIP modulates the stability of GPx4 by linear ubiquitination

LUBAC-mediated linear ubiquitination plays a pivotal role in regulation of cell death and inflammatory pathways. Genetic deficiency in LUBAC components leads to severe immune dysfunction or embryonic lethality. LUBAC has been extensively studied for its role in mediating TNF signaling. However, Tnfr...

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Detalles Bibliográficos
Autores principales: Dong, Kangyun, Wei, Ran, Jin, Taijie, Zhang, Mengmeng, Shen, Jiali, Xiang, Huaijiang, Shan, Bing, Yuan, Junying, Li, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636971/
https://www.ncbi.nlm.nih.gov/pubmed/36279464
http://dx.doi.org/10.1073/pnas.2214227119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636971/
https://www.ncbi.nlm.nih.gov/pubmed/36279464
http://dx.doi.org/10.1073/pnas.2214227119

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