An inhibitor of BRD4, GNE987, inhibits the growth of glioblastoma cells by targeting C-Myc and S100A16

PURPOSE: Among children, glioblastomas (GBMs) are a relatively common type of brain tumor. BRD4 expression was elevated in GBM and negatively correlated with the prognosis of glioma. We investigated the anti-GBM effects of a novel BRD4 inhibitor GNE987. METHODS: We evaluated the anti-tumor effect of...

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Detalles Bibliográficos
Autores principales: Ma, Liya, Li, Gen, Yang, Tianquan, Zhang, Li, Wang, Xinxin, Xu, Xiaowen, Ni, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637061/
https://www.ncbi.nlm.nih.gov/pubmed/36224471
http://dx.doi.org/10.1007/s00280-022-04483-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637061/
https://www.ncbi.nlm.nih.gov/pubmed/36224471
http://dx.doi.org/10.1007/s00280-022-04483-7

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