Cargando…

Characterization of exposure–response relationships of ipatasertib in patients with metastatic castration-resistant prostate cancer in the IPATential150 study

PURPOSE: The exposure–response relationships for efficacy and safety of ipatasertib, a selective AKT kinase inhibitor, were characterized using data collected from 1101 patients with metastatic castration-resistant prostate cancer in the IPATential150 study (NCT03072238). METHODS: External validatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Kotani, Naoki, Wilkins, Justin J., Wade, Janet R., Dang, Steve, Sutaria, Dhruvitkumar S., Yoshida, Kenta, Sundrani, Sameer, Ding, Hao, Garcia, Josep, Hinton, Heather, Sane, Rucha, Chanu, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637074/
https://www.ncbi.nlm.nih.gov/pubmed/36305957
http://dx.doi.org/10.1007/s00280-022-04488-2