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Characterization of exposure–response relationships of ipatasertib in patients with metastatic castration-resistant prostate cancer in the IPATential150 study
PURPOSE: The exposure–response relationships for efficacy and safety of ipatasertib, a selective AKT kinase inhibitor, were characterized using data collected from 1101 patients with metastatic castration-resistant prostate cancer in the IPATential150 study (NCT03072238). METHODS: External validatio...
Autores principales: | Kotani, Naoki, Wilkins, Justin J., Wade, Janet R., Dang, Steve, Sutaria, Dhruvitkumar S., Yoshida, Kenta, Sundrani, Sameer, Ding, Hao, Garcia, Josep, Hinton, Heather, Sane, Rucha, Chanu, Pascal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637074/ https://www.ncbi.nlm.nih.gov/pubmed/36305957 http://dx.doi.org/10.1007/s00280-022-04488-2 |
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