Structural basis for the activation of the lipid scramblase TMEM16F

TMEM16F, a member of the conserved TMEM16 family, plays a central role in the initiation of blood coagulation and the fusion of trophoblasts. The protein mediates passive ion and lipid transport in response to an increase in intracellular Ca(2+). However, the mechanism of how the protein facilitates...

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Detalles Bibliográficos
Autores principales: Arndt, Melanie, Alvadia, Carolina, Straub, Monique S., Clerico Mosina, Vanessa, Paulino, Cristina, Dutzler, Raimund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637102/
https://www.ncbi.nlm.nih.gov/pubmed/36335104
http://dx.doi.org/10.1038/s41467-022-34497-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637102/
https://www.ncbi.nlm.nih.gov/pubmed/36335104
http://dx.doi.org/10.1038/s41467-022-34497-x

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