The use of machine learning modeling, virtual screening, molecular docking, and molecular dynamics simulations to identify potential VEGFR2 kinase inhibitors

Targeting the signaling pathway of the Vascular endothelial growth factor receptor-2 is a promising approach that has drawn attention in the quest to develop novel anti-cancer drugs and cardiovascular disease treatments. We construct a screening pipeline using machine learning classification integra...

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Detalles Bibliográficos
Autores principales: Salimi, Abbas, Lim, Jong Hyeon, Jang, Jee Hwan, Lee, Jin Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637137/
https://www.ncbi.nlm.nih.gov/pubmed/36335233
http://dx.doi.org/10.1038/s41598-022-22992-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637137/
https://www.ncbi.nlm.nih.gov/pubmed/36335233
http://dx.doi.org/10.1038/s41598-022-22992-6

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