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SMG6 regulates DNA damage and cell survival in Hippo pathway kinase LATS2-inactivated malignant mesothelioma

Many genes responsible for Malignant mesothelioma (MM) have been identified as tumor suppressor genes and it is difficult to target these genes directly at a molecular level. We searched for the gene which showed synthetic lethal phenotype with LATS2, one of the MM causative genes and one of the kin...

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Detalles Bibliográficos
Autores principales: Suzuki, Koya, Tange, Masaki, Yamagishi, Ryota, Hanada, Hiroyuki, Mukai, Satomi, Sato, Tatsuhiro, Tanaka, Takeshi, Akashi, Tomohiro, Kadomatsu, Kenji, Maeda, Tohru, Miida, Takashi, Takeuchi, Ichiro, Murakami, Hiroshi, Sekido, Yoshitaka, Murakami-Tonami, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637146/
https://www.ncbi.nlm.nih.gov/pubmed/36335095
http://dx.doi.org/10.1038/s41420-022-01232-w