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Learning the histone codes with large genomic windows and three-dimensional chromatin interactions using transformer

The quantitative characterization of the transcriptional control by histone modifications has been challenged by many computational studies, but most of them only focus on narrow and linear genomic regions around promoters, leaving a room for improvement. We present Chromoformer, a transformer-based...

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Detalles Bibliográficos
Autores principales: Lee, Dohoon, Yang, Jeewon, Kim, Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637148/
https://www.ncbi.nlm.nih.gov/pubmed/36335101
http://dx.doi.org/10.1038/s41467-022-34152-5