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Learning the histone codes with large genomic windows and three-dimensional chromatin interactions using transformer
The quantitative characterization of the transcriptional control by histone modifications has been challenged by many computational studies, but most of them only focus on narrow and linear genomic regions around promoters, leaving a room for improvement. We present Chromoformer, a transformer-based...
Autores principales: | Lee, Dohoon, Yang, Jeewon, Kim, Sun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637148/ https://www.ncbi.nlm.nih.gov/pubmed/36335101 http://dx.doi.org/10.1038/s41467-022-34152-5 |
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