ACE2 N-glycosylation modulates interactions with SARS-CoV-2 spike protein in a site-specific manner

SARS-CoV-2 has evolved continuously and accumulated spike mutations with each variant having a different binding for the cellular ACE2 receptor. It is not known whether the interactions between such mutated spikes and ACE2 glycans are conserved among different variant lineages. Here, we focused on t...

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Detalles Bibliográficos
Autores principales: Isobe, Ayana, Arai, Yasuha, Kuroda, Daisuke, Okumura, Nobuaki, Ono, Takao, Ushiba, Shota, Nakakita, Shin-ichi, Daidoji, Tomo, Suzuki, Yasuo, Nakaya, Takaaki, Matsumoto, Kazuhiko, Watanabe, Yohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637154/
https://www.ncbi.nlm.nih.gov/pubmed/36335195
http://dx.doi.org/10.1038/s42003-022-04170-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637154/
https://www.ncbi.nlm.nih.gov/pubmed/36335195
http://dx.doi.org/10.1038/s42003-022-04170-6

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