A biomimetic electrostatic assistance for guiding and promoting N-terminal protein chemical modification

The modification of protein electrostatics by phosphorylation is a mechanism used by cells to promote the association of proteins with other biomolecules. In this work, we show that introducing negatively charged phosphoserines in a reactant is a powerful means for directing and accelerating the che...

Descripción completa

Detalles Bibliográficos
Autores principales: Ollivier, Nathalie, Sénéchal, Magalie, Desmet, Rémi, Snella, Benoît, Agouridas, Vangelis, Melnyk, Oleg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637170/
https://www.ncbi.nlm.nih.gov/pubmed/36335111
http://dx.doi.org/10.1038/s41467-022-34392-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637170/
https://www.ncbi.nlm.nih.gov/pubmed/36335111
http://dx.doi.org/10.1038/s41467-022-34392-5

Ejemplares similares