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A biomimetic electrostatic assistance for guiding and promoting N-terminal protein chemical modification
The modification of protein electrostatics by phosphorylation is a mechanism used by cells to promote the association of proteins with other biomolecules. In this work, we show that introducing negatively charged phosphoserines in a reactant is a powerful means for directing and accelerating the che...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637170/ https://www.ncbi.nlm.nih.gov/pubmed/36335111 http://dx.doi.org/10.1038/s41467-022-34392-5 |