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Parent-of-Origin inference for biobanks

Identical genetic variations can have different phenotypic effects depending on their parent of origin. Yet, studies focusing on parent-of-origin effects have been limited in terms of sample size due to the lack of parental genomes or known genealogies. We propose a probabilistic approach to infer t...

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Detalles Bibliográficos
Autores principales: Hofmeister, Robin J., Rubinacci, Simone, Ribeiro, Diogo M., Buil, Alfonso, Kutalik, Zoltán, Delaneau, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637181/
https://www.ncbi.nlm.nih.gov/pubmed/36335127
http://dx.doi.org/10.1038/s41467-022-34383-6