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Parent-of-Origin inference for biobanks
Identical genetic variations can have different phenotypic effects depending on their parent of origin. Yet, studies focusing on parent-of-origin effects have been limited in terms of sample size due to the lack of parental genomes or known genealogies. We propose a probabilistic approach to infer t...
Autores principales: | Hofmeister, Robin J., Rubinacci, Simone, Ribeiro, Diogo M., Buil, Alfonso, Kutalik, Zoltán, Delaneau, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637181/ https://www.ncbi.nlm.nih.gov/pubmed/36335127 http://dx.doi.org/10.1038/s41467-022-34383-6 |
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