Cargando…

FRET-FISH probes chromatin compaction at individual genomic loci in single cells

Chromatin compaction is a key biophysical property that influences multiple DNA transactions. Lack of chromatin accessibility is frequently used as proxy for chromatin compaction. However, we currently lack tools for directly probing chromatin compaction at individual genomic loci. To fill this gap,...

Descripción completa

Detalles Bibliográficos
Autores principales: Mota, Ana, Berezicki, Szymon, Wernersson, Erik, Harbers, Luuk, Li-Wang, Xiaoze, Gradin, Katarina, Peuckert, Christiane, Crosetto, Nicola, Bienko, Magda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637210/
https://www.ncbi.nlm.nih.gov/pubmed/36335096
http://dx.doi.org/10.1038/s41467-022-34183-y