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An adherent-invasive Escherichia coli-colonized mouse model to evaluate microbiota-targeting strategies in Crohn's disease

Adherent-invasive Escherichia coli (AIEC) were investigated for their involvement in the induction/chronicity of intestinal inflammation in Crohn's disease (CD). AIEC gut establishment is favoured by overexpression of the glycoprotein CEACAM6 in the ileal epithelium. We generated a transgenic m...

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Detalles Bibliográficos
Autores principales: Sivignon, Adeline, Chervy, Mélissa, Chevarin, Caroline, Ragot, Elia, Billard, Elisabeth, Denizot, Jérémy, Barnich, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637268/
https://www.ncbi.nlm.nih.gov/pubmed/36172858
http://dx.doi.org/10.1242/dmm.049707