Metformin suppresses vascular smooth muscle cell senescence by promoting autophagic flux

INTRODUCTION: Vascular smooth muscle cell (VSMC) senescence in the vasculature results in vascular aging as well as age-related diseases, while metformin improves the inflamm-aging profile by enhancing autophagy. However, metformin’s impact on VSMC senescence is largely undefined. OBJECTIVES: To tes...

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Detalles Bibliográficos
Autores principales: Tai, Shi, Sun, Jiaxing, Zhou, Yuying, Zhu, Zhaowei, He, Yuhu, Chen, Mingxian, Yang, Hui, Xiao, Yichao, Tu, Tao, Tang, Liang, Li, Xuping, Zeng, Jianping, Zheng, Xilong, Zhou, Shenghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637479/
https://www.ncbi.nlm.nih.gov/pubmed/36328749
http://dx.doi.org/10.1016/j.jare.2021.12.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637479/
https://www.ncbi.nlm.nih.gov/pubmed/36328749
http://dx.doi.org/10.1016/j.jare.2021.12.009

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