A substrate-induced gating mechanism is conserved among Gram-positive IgA1 metalloproteases

The mucosal adaptive immune response is dependent on the production of IgA antibodies and particularly IgA1, yet opportunistic bacteria have evolved mechanisms to specifically block this response by producing IgA1 proteases (IgA1Ps). Our lab was the first to describe the structures of a metal-depend...

Descripción completa

Detalles Bibliográficos
Autores principales: Redzic, Jasmina S., Rahkola, Jeremy, Tran, Norman, Holyoak, Todd, Lee, Eunjeong, Martín-Galiano, Antonio Javier, Meyer, Nancy, Zheng, Hongjin, Eisenmesser, Elan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637739/
https://www.ncbi.nlm.nih.gov/pubmed/36336763
http://dx.doi.org/10.1038/s42003-022-04173-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637739/
https://www.ncbi.nlm.nih.gov/pubmed/36336763
http://dx.doi.org/10.1038/s42003-022-04173-3

Ejemplares similares