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A substrate-induced gating mechanism is conserved among Gram-positive IgA1 metalloproteases
The mucosal adaptive immune response is dependent on the production of IgA antibodies and particularly IgA1, yet opportunistic bacteria have evolved mechanisms to specifically block this response by producing IgA1 proteases (IgA1Ps). Our lab was the first to describe the structures of a metal-depend...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637739/ https://www.ncbi.nlm.nih.gov/pubmed/36336763 http://dx.doi.org/10.1038/s42003-022-04173-3 |