Generation and characterization of a novel gne Knockout Model in Zebrafish

GNE Myopathy is a rare, recessively inherited neuromuscular worldwide disorder, caused by a spectrum of bi-allelic mutations in the human GNE gene. GNE encodes a bi-functional enzyme responsible for the rate-limiting step of sialic acid biosynthesis pathway. However, the process in which GNE mutatio...

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Detalles Bibliográficos
Autores principales: Livne, Hagay, Avital, Tom, Ruppo, Shmuel, Harazi, Avi, Mitrani-Rosenbaum, Stella, Daya, Alon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637792/
https://www.ncbi.nlm.nih.gov/pubmed/36353515
http://dx.doi.org/10.3389/fcell.2022.976111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637792/
https://www.ncbi.nlm.nih.gov/pubmed/36353515
http://dx.doi.org/10.3389/fcell.2022.976111

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