Artemisinin derivative DHA27 enhances the antibacterial effect of aminoglycosides against Pseudomonas aeruginosa by inhibiting mRNA expression of aminoglycoside-modifying enzymes

Bacterial resistance is becoming increasingly serious, the present study aimed to investigate the mechanism of antibacterial sensitization effect of DHA27 combined with tobramycin in tobramycin-resistant Pseudomonas aeruginosa (PA). We found that DHA27 combined with aminoglycosides had an antibacter...

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Detalles Bibliográficos
Autores principales: Wang, Nuoyan, Chen, Xuemin, Luo, Jing, Deng, Fei, Shi, Fuguo, Wu, Qin, Huang, Yasi, Ouyang, Qin, Qin, Rongxin, Zhou, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637796/
https://www.ncbi.nlm.nih.gov/pubmed/36353502
http://dx.doi.org/10.3389/fphar.2022.970400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637796/
https://www.ncbi.nlm.nih.gov/pubmed/36353502
http://dx.doi.org/10.3389/fphar.2022.970400

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