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Combining metformin with lactate transport inhibitors as a treatment modality for cancer - recommendation proposal
Highly glycolytic cancer cells excrete lactate to maintain cellular homeostasis. Inhibiting lactate export by pharmacological targeting of plasma membrane lactate transporters is being pursued as an anti-cancer therapy. Work from many laboratories show that the simultaneous inhibition of lactate exp...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637960/ https://www.ncbi.nlm.nih.gov/pubmed/36353534 http://dx.doi.org/10.3389/fonc.2022.1034397 |