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Chaigui granule exerts anti-depressant effects by regulating the synthesis of Estradiol and the downstream of CYP19A1-E2-ERKs signaling pathway in CUMS-induced depressed rats

Background: There is a significant gender difference in the prevalence of depression. Recent studies have shown that estrogen plays a crucial role in depression. Therefore, studying the specific mechanism of estrogen’s role in depression can provide new ideas to address the treatment of depression....

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Detalles Bibliográficos
Autores principales: Tian, Jun-sheng, Qin, Peng-fei, Xu, Teng, Gao, Yao, Zhou, Yu-zhi, Gao, Xiao-xia, Qin, Xue-mei, Ren, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637986/
https://www.ncbi.nlm.nih.gov/pubmed/36353500
http://dx.doi.org/10.3389/fphar.2022.1005438