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Functional rewiring of G protein-coupled receptor signaling in human labor

Current strategies to manage preterm labor center around inhibition of uterine myometrial contractions, yet do not improve neonatal outcomes as they do not address activation of inflammation. Here, we identify that during human labor, activated oxytocin receptor (OTR) reprograms the prostaglandin E2...

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Detalles Bibliográficos
Autores principales: Walker, Abigail R., Larsen, Camilla B., Kundu, Samit, Stavrinidis, Christina, Kim, Sung Hye, Inoue, Asuka, Woodward, David F., Lee, Yun S., Migale, Roberta, MacIntyre, David A., Terzidou, Vasso, Fanelli, Francesca, Khanjani, Shirin, Bennett, Phillip R., Hanyaloglu, Aylin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638024/
https://www.ncbi.nlm.nih.gov/pubmed/36070698
http://dx.doi.org/10.1016/j.celrep.2022.111318