Cargando…
Functional rewiring of G protein-coupled receptor signaling in human labor
Current strategies to manage preterm labor center around inhibition of uterine myometrial contractions, yet do not improve neonatal outcomes as they do not address activation of inflammation. Here, we identify that during human labor, activated oxytocin receptor (OTR) reprograms the prostaglandin E2...
Autores principales: | Walker, Abigail R., Larsen, Camilla B., Kundu, Samit, Stavrinidis, Christina, Kim, Sung Hye, Inoue, Asuka, Woodward, David F., Lee, Yun S., Migale, Roberta, MacIntyre, David A., Terzidou, Vasso, Fanelli, Francesca, Khanjani, Shirin, Bennett, Phillip R., Hanyaloglu, Aylin C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638024/ https://www.ncbi.nlm.nih.gov/pubmed/36070698 http://dx.doi.org/10.1016/j.celrep.2022.111318 |
Ejemplares similares
-
Prostaglandin F2α requires activation of calcium-dependent signalling to trigger inflammation in human myometrium
por: Riaposova, Lucia, et al.
Publicado: (2023) -
Nuclear Factor Kappa B Activation Occurs in the Amnion Prior to Labour Onset and Modulates the Expression of Numerous Labour Associated Genes
por: Lim, Sheri, et al.
Publicado: (2012) -
NFκB and AP-1 Drive Human Myometrial IL8 Expression
por: Khanjani, Shirin, et al.
Publicado: (2012) -
Whole Blood Holding Time Prior to Plasma Processing Alters microRNA Expression Profile
por: Kim, Sung Hye, et al.
Publicado: (2022) -
Oxytocin Receptor Antagonists, Atosiban and Nolasiban, Inhibit Prostaglandin F(2α)-induced Contractions and Inflammatory Responses in Human Myometrium
por: Kim, Sung Hye, et al.
Publicado: (2019)