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Parthenolide and arsenic trioxide co-trigger autophagy-accompanied apoptosis in hepatocellular carcinoma cells

Although arsenic trioxide (ATO) shows a strong anti-tumor effect in the treatment of acute promyelocytic leukemia, it does not benefit patients with hepatocellular carcinoma (HCC). Thus, combination therapy is proposed to enhance the efficacy of ATO. Parthenolide (PTL), a natural compound, selective...

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Detalles Bibliográficos
Autores principales: Yi, Juan, Gong, Xia, Yin, Xiao-Yang, Wang, Li, Hou, Jin-Xia, Chen, Jing, Xie, Bei, Chen, Gang, Wang, Li-Na, Wang, Xiao-Yuan, Wang, Da-Chun, Wei, Hu-Lai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638029/
https://www.ncbi.nlm.nih.gov/pubmed/36353537
http://dx.doi.org/10.3389/fonc.2022.988528