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Munc18-1 Contributes to Hippocampal Injury in Septic Rats Through Regulation of Syntanxin1A and Synaptophysin and Glutamate Levels

Sepsis-associated encephalopathy (SAE) is a diffuse brain dysfunction closely associated with mortality in the acute phase of sepsis. Abnormal neurotransmitters release, such as glutamate, plays a crucial role in the pathological mechanism of SAE. Munc18-1 is a key protein regulating neurotransmissi...

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Detalles Bibliográficos
Autores principales: Tang, Fajuan, Chen, Lin, Gao, Hu, Lei, Yupeng, Pan, Linli, Xiao, Dongqiong, Li, Xihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638283/
https://www.ncbi.nlm.nih.gov/pubmed/36335177
http://dx.doi.org/10.1007/s11064-022-03806-7