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Transcriptomic analysis of the human placenta reveals trophoblast dysfunction and augmented Wnt signalling associated with spontaneous preterm birth

Preterm birth (PTB) is the leading cause of death in under-five children. Worldwide, annually, over 15 million babies are born preterm and 1 million of them die. The triggers and mechanisms of spontaneous PTB remain largely unknown. Most current therapies are ineffective and there is a paucity of re...

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Detalles Bibliográficos
Autores principales: Akram, Khondoker M., Kulkarni, Neha S., Brook, Abbey, Wyles, Matthew D., Anumba, Dilly O. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638416/
https://www.ncbi.nlm.nih.gov/pubmed/36353514
http://dx.doi.org/10.3389/fcell.2022.987740