Cargando…
Transcriptomic analysis of the human placenta reveals trophoblast dysfunction and augmented Wnt signalling associated with spontaneous preterm birth
Preterm birth (PTB) is the leading cause of death in under-five children. Worldwide, annually, over 15 million babies are born preterm and 1 million of them die. The triggers and mechanisms of spontaneous PTB remain largely unknown. Most current therapies are ineffective and there is a paucity of re...
Autores principales: | Akram, Khondoker M., Kulkarni, Neha S., Brook, Abbey, Wyles, Matthew D., Anumba, Dilly O. C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638416/ https://www.ncbi.nlm.nih.gov/pubmed/36353514 http://dx.doi.org/10.3389/fcell.2022.987740 |
Ejemplares similares
-
Impaired autophagy with augmented apoptosis in a Th1/Th2-imbalanced placental micromilieu is associated with spontaneous preterm birth
por: Akram, Khondoker M., et al.
Publicado: (2022) -
Spectral binning of cervicovaginal fluid metabolites improves prediction of spontaneous preterm birth and Lactobacillus species dominance
por: Amabebe, Emmanuel, et al.
Publicado: (2021) -
The diversity of trophoblast cells and niches of placenta accreta spectrum disorders revealed by single-cell RNA sequencing
por: Ma, Jingmei, et al.
Publicado: (2022) -
The Metabolomic Signature of the Placenta in Spontaneous Preterm Birth
por: Elshenawy, Summer, et al.
Publicado: (2020) -
Dynamics of Tryptophan Metabolic Pathways in Human Placenta and Placental-Derived Cells: Effect of Gestation Age and Trophoblast Differentiation
por: Karahoda, Rona, et al.
Publicado: (2020)