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Galcanezumab modulates Capsaicin-induced C-fiber reactivity

BACKGROUND: The vasodilatory calcitonin-gene related peptide (CGRP) is understood as pivotal mediator in migraine pathophysiology. Blocking CGRP with small molecules or monoclonal antibodies (CGRP-mAb) reduces migraine frequency. However, prescription of CGRP-mAbs is still regulated and possible pre...

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Detalles Bibliográficos
Autores principales: Basedau, Hauke, Oppermann, Thalea, Gundelwein Silva, Elisa, Peng, Kuan-Po, May, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638712/
https://www.ncbi.nlm.nih.gov/pubmed/35796521
http://dx.doi.org/10.1177/03331024221112906