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The potential effects and mechanisms of Gegen Qinlian Decoction in oxaliplatin-resistant colorectal cancer based on network pharmacology

BACKGROUND: Resistance to chemotherapeutic drugs, such as oxaliplatin (OXA), can lead to unsatisfactory chemotherapy results during the treatment of advanced colorectal cancer (CRC). Therefore, we investigated the potential targets and mechanisms of Gegen Qinlian Decoction (GQD) against OXA-resistan...

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Detalles Bibliográficos
Autores principales: Lin, Xiang, Xu, Li, Tan, Huicheng, Zhang, Xinyi, Shao, Huan, Yao, Li, Huang, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638763/
https://www.ncbi.nlm.nih.gov/pubmed/36353164
http://dx.doi.org/10.1016/j.heliyon.2022.e11305