A NANOG‐pERK reciprocal regulatory circuit regulates Nanog autoregulation and ERK signaling dynamics

The self‐renewal and differentiation potential of embryonic stem cells (ESCs) is maintained by the regulated expression of core pluripotency factors. Expression levels of the core pluripotency factor Nanog are tightly regulated by a negative feedback autorepression loop. However, it remains unclear...

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Detalles Bibliográficos
Autores principales: Kale, Hanuman T, Rajpurohit, Rajendra Singh, Jana, Debabrata, Vishnu, Vijay V, Srivastava, Mansi, Mourya, Preeti R, Srinivas, Gunda, Shekar, P Chandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638859/
https://www.ncbi.nlm.nih.gov/pubmed/36066347
http://dx.doi.org/10.15252/embr.202154421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638859/
https://www.ncbi.nlm.nih.gov/pubmed/36066347
http://dx.doi.org/10.15252/embr.202154421

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