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The chromatin remodeler RSC prevents ectopic CENP-A propagation into pericentromeric heterochromatin at the chromatin boundary

Centromeres of most eukaryotes consist of two distinct chromatin domains: a kinetochore domain, identified by the histone H3 variant, CENP-A, and a heterochromatic domain. How these two domains are separated is unclear. Here, we show that, in Schizosaccharomyces pombe, mutation of the chromatin remo...

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Detalles Bibliográficos
Autores principales: Tsunemine, Satoru, Nakagawa, Hiromi, Suzuki, Yutaka, Murakami, Yota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638902/
https://www.ncbi.nlm.nih.gov/pubmed/36200823
http://dx.doi.org/10.1093/nar/gkac827